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Biological impact of metallic nanoparticles

 
Competition calendar April 2020
Investigating biological impact of inhalation exposure to metallic nanoparticles

As part of an experimental study on the biological impact of inhalation exposures, we studied the distribution of metal particles in rodent upper airways and lungs. Single Ion Mass Spectrometry microscopy was used to detect these particles in situ after repeated inhalation of a polydisperse aerosol. Results are presented on microphotographs of olfactory epithelium and lung sections.

Image 1 - Structural representation of the olfactory epithelium, superimposed ion images of metal particle in red and 40Ca+ in blue field of view 100 x 100 μm2. White arrows show the metal particle.
Image 2 - Structural representation of the pulmonary system, superimposed ion images of metal particle in red and 40Ca+ in blue field of view 200 x 200 μm2 White arrows show the metal particle.


Recorded on CAMECA IMS 7f at IRSN Laboratory, Fontenay-aux-Roses, France.
Image courtesy of D. Suhard.

Winning image for the month of April 2020