The replacement of bone plays a crucial role in various modern medical procedures. The success of surgical interventions and the longevity of the implant components are primarily influenced by the biocompatibility of the implanted devices, how well they interact with surrounding tissues.
A research team at the University of Sydney demonstrated the potential of Atom Probe Tomography in studying the integration and element transfer between synthetic bone (specifically, 3D-printed strontium hardystonite gahnite bioceramic scaffolds) and surrounding tissue in a 12-month in vivo sheep model.
This work represents some of the first APT applications to in vivo ceramic implants, demonstrating ion migration from the bone scaffold material itself into bone tissue.
Read the application note:
Biomedical Applications of Atom Probe Tomography: Developing APT for bone tissue repair medical devices
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