NanoSIMS 50L

应用于高空间分辨率下同位素和痕量元素分析的SIMS探针
NanoSIMS 50L是一款独特的离子探针,在高横向分辨率下优化了SIMS分析性能。该仪器的开发借鉴了离子束和二次离子提取的同轴光学设计以及具有多接收功能的原始扇形磁质量分析仪。
  • 产品概述 +


    NanoSIMS 50L能同时提供关键性能,而使用任何其他已知的仪器或技术只能部分提供这些性能:
    • 高分析空间分辨率(低至50纳米)
    • 高灵敏度(元素成像中的ppm)
    • 高质量分辨率(M/dM)
    • 并行采集七种不同质荷比离子
    • 快速采集(直流模式,不发生脉冲)
    • 能够分析电绝缘样品
    经最新改良,现在可实现千分之十几的同位素比值再现性。

    扩展应用领域

    微生物学

    NanoSIMS 50L为环境中混合微生物群落研究中的单细胞系统发育特征(使用FISH或El-FISH)和代谢功能(使用稳定同位素标记)的结合开辟了新的可能性。

    细胞生物学:
    NanoSIMS 50L具备50纳米分辨率和测定同位素比值功能,可实现对细胞内带有稳定同位素标记的分子的积累和传输的测量。

    地质学和空间科学:
    NanoSIMS 50L可以对行星际尘埃颗粒、陨石和矿物部分的亚微米区域、晶粒或包裹体进行精确的同位素和元素测量。该仪器在多个法拉第杯配置下工作,并具有几微米的光斑尺寸,可以提供同位素比值测量,具有极高精确度以及低至千分之十几的的外部再现性。

    材料研究:
    凭借高质量分辨率下的高灵敏度(无质量干扰),即使在电绝缘材料中,NanoSIMS 50L也可以在50纳米SIMS横向分辨率下进行痕量元素(掺杂物)成像和定量分析。除稀有气体以外的所有元素(从氢到钚)均可测量。

    NanoSIMS 50L最初由法国巴黎第十一大学的G. Slodzian教授设计。
  • 看看NanoSIMS能够做什么 +

  • 下载文档 +

  • NanoSIMS出版物 +


    现有引用NanoSIMS数据的科学研究文章的汇总Excel电子表格可供下载。这些文章按以下主要应用领域进行分类,并且可以使用Excel字词搜索功能轻松搜索:

    • 大气颗粒/气溶胶
    • 生物矿化/古气候
    • 细胞生物学
    • 环境微生物学
    • 地质学/环境学
    • 地质年代学
    • 古生物学/进化论
    • 化妆品和药理学
    • 行星科学
    • 植物
    • 土壤
    • 材料
    • 仪器/方法学
    点击此处下载电子表格:NanoSIMS科学文章汇总(最后更新日期:2017年11月12日)。

    如果您无法打开部分PDF文件,请随时通过电子邮件(cameca.info@ametek.com)联系我们。如果您有其他相关参考资料、PDF和补充信息,请发送给我们!
  • Webinars +

  • NanoSIMS遍布全球的用户 +

    Below are links to some of our NanoSIMS Users
    If your site is not listed and you would like to appear on this page, please contact cameca.info@ametek.com.

    Stanford Nano Shared Facilities (SNSF), CA, USA
    NSF provides shared scientific instrumentation, laboratory facilities, and expert staff support to enable multidisciplinary research and educate tomorrow’s scientists and engineers.

    NASA, Astromaterials Research & Exploration Science, Houston TX, USA
    The ARES scientists are dedicated to astromaterials research (meteorites, cosmic and interplanetary dust, solar wind, and lunar rocks), exobiology & organic geochemistry. They use a NanoSIMS 50L to uncover insights on processes of early solar system and stellar evolution.

    Lawrence Livermore National Laboratory, California, USA
    The NanoSIMS at LLNL is used in groundbreaking microbiological research: it helps studying microbial nitrogen and carbon fixation, and carbon cycling, investigating forensic signatures in bacterial spores, vegetative cells, viruses, as well as a range of nuclear materials..

    CalTech Center for Microanalysis, USA
    The Center for Microanalysis at Caltech houses a NanoSIMS 50L and an IMS 7f-GEO, providing expertise for microanalysis of geological, meteoritic and synthetic materials. Research projects carried out at CCM are most varied, ranging from cosmochemistry to experimental studies on climate change, geochronology, in-situ studies of microbial communities, materials science engineering, and more...

    Center for NanoImaging, Brigham and Women's Hospital, USA
    Our mission is to extend multi-isotope imaging mass spectrometry – or MIMS – to new areas of biology and biomedical research, including with human translational studies conducted at the Brigham and Women’s Hospital and collaborating medical centers.

    Arizona State University, Tempe, USA

    Funded by the National Science Foundation and ASU, the NanoSIMS lab at ASU is mainly in space sciences, to investigate the chemistry of asteroids and comets.

    Washington University in Saint-Louis, MI, USA
    The Laboratory for Space Sciences at Washington University received the first NanoSIMS in 2000. Research projects cover presolar grains, interplanetary dust particles, meteorite geochemistry etc.

    Environmental Molecular Science Laboratory, Richland, WA, USA
    EMSL, a national scientific user facility at Pacific Northwest National Laboratory has been equipped with a NanoSIMS 50L model since 2011.
    > Watch video on Air particle research at EMSL

    Manchester University, School of Materials, UK
    The NanoSIMS 50L is a major component of the Multi-Disciplinary Characterisation Facility, and is applied across a wide range of projects in advanced materials research, geological investigations of interest to the nuclear,oil and gas sectors, as well as the study of extra-terrestrial materials, but also tracing biochemical processes in microbes and plants.

    Open University, UK
    The NanoSIMS 50L lab in Milton Keynes is managed by Dr I.A. Franchi, and used primarily for characterizing fine grained material and cometary dust particles collected in the stratosphere.

    The Department of Materials, University of Oxford, UK
    The CAMECA NanoSIMS 50 is an ultra high resolution chemical imaging facility combining the sensitivity of a dynamic SIMS with a lateral resolution of about 100nm. Our machine was delivered in August 2002 and is used on a very wide range of projects in the analysis of metallic, semiconducting, polymeric and biological materials....

    Max Planck Institute for Chemistry, Cosmochemistry Department, Mainz, Germany
    The Cosmochemistry Department consists of several groups of scientists and technical personnel whose research interests and activities span a wide variety of fields in cosmochemical and space sciences. Many abstracts in the astrophysics field, downloadable in pdf format

    Max Planck Institut, Bremen, Germany

    The Max Planck Institute for Marine Microbiology of Bremen hosts the first NanoSIMS dedicated to environmental microbiology.

    Leibniz Institute for Baltic Sea Research (IOW), Warnemünde, Germany
    The NanoSIMS 50L at IOW is applied to a wide range of research fiels from microbiology and medicine to particle analysis and soil science.

    TUM: Technische Universität München, Germany
    Research Department Ecology and Ecosystem Management. Soil is the focal and connecting link between the information, matter and energy cycles of the hydrogeosphere and the atmosphere. Soil organic matter, clay sized particles and iron oxides are the most important reactants in soils building a complex physico-chemical interface. (…)

    Helmholtz Centre for Environmental Research – UFZ Leipzig, Germany
    Department of Isotope Biogeochemistry.
    What is the role of biogeochemical processes in the functionality of sustainably managed ecosystems? How can stable isotope readings assist the understanding of the fate of chemicals in anoxic environments such as soil-aquifer systems, freshwater and deep-sea sediments and bioreactors?

    University Medical Center Goettingen (UMG), Germany

    The University of Göttingen NanoSIMS was acquired in 2017 to equip the Center for Biostructural Imaging of Neurodeegneration (BIN).It is mainly applied to  the imaging of specific biological organelles, and thus provides insights into local protein and organelle turnover in a variety of cells and tissues.

    Faculty of Life Science, University of Vienna, Austria
    Inaugurated in February 2010, the NanoSIMS 50L lab is located within the Core Facility for Advanced Isotope Research. Under leadership from Michael Wagner, the Department of Microbial Ecology is one of the world leading center for single cell microbiology and the study of microorganisms in selected ecosystems.

    UPFL: Université Polytechnique Fédérale de Lausanne, Switzerland
    Laboratory for Biological Geochemistry LGB. Established in 2012, the LBG currently consists of about 15 Senior Scientists, Postdocs, PhD- and Master students working on research projects at the interface between isotope geochemistry, mineralogy and biology.

    LIST, Luxembourg institute of Science and Technology, Luxembourg
    The Luxembourg Institute of Science and Technology (LIST) is a mission-driven Research and Technology Organisation (RTO) that develops advanced technologies and delivers innovative products and services to industry and society.

    Utrecht University, Netherlands
    Since summer 2013 Utrecht University hosts the Dutch national facility for high-resolution in situ isotope and element analysis of natural materials, supporting research in biogeochemistry and (microbial) ecology, paleo-environmental and climate reconstructions, planetary and solid earth sciences.
    > Watch video on NanoSIMS

    Institut de Minéralogie, de Physique des Matériaux et de Cosmochimie (IMPMC), Paris, France
    The IMPMC is particularly notable in its multidisciplinary approach. This means most topics are studied by researchers from different backgrounds—in physics, Earth science or biology. Experimental platforms, technical know-how and scientific expertise are all used to conduct research on the interactions between the living world (including bacteria) and the mineral world.

    Institut Curie, Orsay, France
    Analytical Imaging of the Cell by Secondary Ion Mass Spectroscopy (SIMS microscopy). Introduction: "Of the various analytical methods developed in microscopy during the latter half of the century, SIMS imaging is probably one of the most powerful and sophisticated. Originally introduced..." Link to full article.

    Groupe de Physique des Matériaux (GPM), Rouen, France
    The NanoSIMS at GPM supports multidisciplinary projects in the field of health and environment: human exposure to nanoparticles and their dispersion in the environment, interactions of (nano)particles with living organisms in connection with toxicological and cosmetological studies.

    IPREM, Université of Pau, France

    The NanoSIMS 50L at Institute of Analytical Sciences and Physico-Chemistry for Environment and Materials (IPREM) is the first one equipped with the new RF Plasma oxygen ion source. It is mainly used for the localization of metals at catalyst surfaces or the imaging of essential and toxic trace metals in biological cells.

    Chalmers University of Technology, Sweden
    The NanoSIMS 50L in Gothenburg is the first of these instruments in Scandinavia. The NanoSIMS is suitable for a wide variety of applications such as grain boundary analysis, characterization of stress corrosion cracking, sub-cellular drug/peptide imaging and nitrogen fixation studies in bacteria.

    Physical Research Laboratory, India
    Known as the cradle of Space Sciences in India, the Physical Research Laboratory (PRL) was founded in 1947 by Dr. Vikram Sarabhai. As a unit of the Department of Space, Government of India, PRL carries out fundamental research in select areas of Physics, Space & Atmospheric Sciences, Astronomy, Astrophysics & Solar Physics, and Planetary & Geosciences.

    IGGCAS, Beijing, China
    The Institute of Geology and Geophysics, Chinese Academy of Sciences houses a NanoSIMS 50L in addition to its 2 large-geometry SIMS (IMS 1280 and IMS 1280-HR). The NanoSIMS was acquired to promote research in space sciences and is meant to play a major role in the analysis of lunar samples retrieved by Chinese lunar exploration missions.

    Academia Sinica, Taipei, Taiwan
    The NanoSIMS Laboratory was established in 2013 by a cooperative effort between Institute of Astronomy and Astrophysics and the Institute of Earth Science of Academia Sinica. Primarily designed to probe the early Solar System by analyzing extraterrestrial and terrestrial samples, the laboratory is also involved in numerous interdisciplinary collaborations with both domestic and international research groups covering cosmo, geo, life and material sciences.

    Kochi Institute for Core Research Sample, JAMSTEC, Japan
    The Isotope Geochemistry Group owns several CAMECA SIMS dedicated to the analysis of isotopes and trace elements in geological, environmental and biological samples to understand water-rock interactions, geologic processes, global & regional geochemical cycles, and limits of subseafloor life.

    Centre for Microscopy, Characterization & Analysis, UWA, Perth, Autralia
    Established in 1970, the CMCA provides essential teaching and research infrastructure in ion, electron, laser and light microscopy and microanalysis to universities, goverment of Western Australia and local industry. It is now home to two CAMECA ion probes, the NanoSIMS 50 installed in 2003 and the more recently acquired IMS 1280.
  • 软件 +

    • WinCurve dataprocessing sofware
      WinCurve

      WinCurve专为CAMECA SIMS仪器而开发,可在用户友好的环境中提供强大的数据处理和可视化功能。

      继续阅读

    • WinImage Software
      WinImage II

      WinImage II专为CAMECA SIMS仪器而开发,可在PC-Windows™环境中提供强大的数据处理和可视化功能。

      继续阅读

    • APM Software
      APM

      自动颗粒测量(APM)是CAMECA推出的一款软件工具,可应用于数百万颗粒的快速筛选、颗粒探测和同位素表征。

      继续阅读

  • 升级套件 +

    PRIMARY COLUMN

    RF-plasma O-:高亮度O-主离子源
    替换duoplasmatron O-离子源。 RF等离子体离子源的较高亮度允许获得与Cs +源相似的O-束密度和横向分辨率。

    D1 5-Slits_NS:五个D1光圈隔膜狭缝
    物镜/浸没式镜头光圈带通过增加4到5种尺寸的直径选择来增加灵活性。

    EXLIE Pre-implant_NS:极低的冲击能量
    超低能量(25-500eV)样品轰击允许预植入/清洁而不消耗超薄样品的顶部表面。

    高电流Column_NS:高电流初级离子柱
    允许更大的最大Cs +电子束电流(最高20nA而不是几个nA)。
    使用更大的电流允许使用多个FC代替EM并提高同位素比重现性。

    真空

    Pfeiffer Turbo:更换三个涡轮分子泵
    用同等的Pfeiffer型号替换三个涡轮分子Varian / Agilent泵,具有出色的可靠性。

    加载锁定生产力增强:如果加载锁定
    替换标准涡轮泵/> 对于需要非计划加载和快速分析的实验室,可以用300 l / s涡轮分子泵代替标准的80 l / s负载锁定涡轮泵。然后,在负载锁定中达到1E-6mbar所需的时间通常从~120分钟减少x3。到~40分钟

    质量分析器

    EM前置放大器Gen2_NS:五个新的EM前置放大器鉴别器
    用于离子计数的电子离子脉冲放大的改进。
    更可靠的设置和鉴别器/阈值的调整,以获得更可重复的同位素比率。

    内部Multico Gen2_NS:新内部多重收藏
    可移动电缆提高了可靠性,减少了短路和堵塞。

    低噪声前置放大器_NS:Multico Geo Faraday:用于FC#1的低噪声前置放大器
    精确的FC-EM同位素比率。
    法拉第杯具有更低的噪声/背景,从而在FC中实现更好的重现性和更大的电流检测范围。

    Multico Triple Faraday_NS:Multicollection triple Faraday
    三个FC而不是一个。
    允许测量具有亚permil再现性的多个FC中的同位素比率,通常记录具有更高(几个nA)和<微米; m点。

    NMR H / D_NS: 氢的附加NMR探针
    低质谱线的稳定性。
    添加了第三个专用的NMR探针,提高了分析仪磁场的稳定性,实现了H比率的高再现性。

    IMAGING

    光学显微镜Gen2_NS:改进的光学显微镜
    更换照明和光学显微镜,实现更均匀的照明,数码相机,更好的分辨率,数码变焦。

    SED_NS: 二次电子探测器
    二次电子成像,用于定位小颗粒和良好的对比度,以补充SIMS成像。

    电子

    32b_Acquisition Board_NS:32位计数板
    取代16bit以前的版本,是使用Team Viewer通过互联网进行远程控制所必需的。
    SIMS图像不再饱和,扫描速度更快,充电问题更少。

    数据系统

    PC automation_NS:PC Windows Control升级
    不再支持SUN系统,取而代之的是PC Windows自动化。
    PC版本下可用的新功能。

    软件版本Update_NS: 更新后的软件版本
    最新的PC自动化版本,用于删除问题,新功能以及某些升级所需的版本。

    Control Duplication_NS:NanoSIMS控件的复制
    从两个房间内的CAMECA设计的键盘,从单独的操作室(<15 m)控制仪器。
    允许优化的操作舒适性(降低噪音,单独的T&deg; C控制)

    其他WinImage II_NS:其他64位WinImage II离线PC软件许可证
    SUN和PC数据的图像处理。适用于多个用户的加密狗。

    自动化

    DUO Auto Valve_NS:Duoplasmatron泄漏阀的自动化
    允许在无人值守采集结束时关闭泄漏阀,使用duoplasmatron在拆卸清洁时更长时间使用双源。

    Full MDA_NS:Aperture和Hexapole Automation
    狭缝自动化&amp;用于提高再现性的孔径,低级别用户的访问,清洁/获取的链接,使用的舒适性。&nbsp;

    样品持有人,SHUTTLES&amp;转移

    Sample-holders_Shuttles_NS:样品架和航天飞机的列表可在此链接获得。
    请联系售后服务部门获取订单。

    磁力转移棒:两个磁力传递杆
    将带有样品架的梭子从装载锁转移到分析台上。

    您还可以查看适用于您的乐器的软件版本

    不要犹豫,联系您的本地代理商或&CAMECA销售部门了解更多信息。